Kappa-symmetric higher derivative terms in brane actions

Using the superembedding formalism we construct supermembrane actions with higher derivative terms which can be viewed as possible higher order terms in effective actions. In particular, we provide the first example of an action for an extended supersymmetric object with fully $\kappa$-symmetric extrinsic curvature terms.Comment: 16 pages, Latex, References adde

Sigma models with off-shell N=(4,4) supersymmetry and noncommuting complex structures

We describe the conditions for extra supersymmetry in N=(2,2) supersymmetric nonlinear sigma models written in terms of semichiral superfields. We find that some of these models have additional off-shell supersymmetry. The (4,4) supersymmetry introduces geometrical structures on the target-space which are conveniently described in terms of Yano f-structures and Magri-Morosi concomitants. On-shell, we relate the new structures to the known bi-hypercomplex structures.Comment: 20 pages; v2: significant corrections, clarifications, and reorganization; v3: discussion of supersymmetry vs twisted supersymmetry added, relevant signs corrected

Palatini Variational Principle for NN-Dimensional Dilaton Gravity

We consider a Palatini variation on a general $N$-Dimensional second order, torsion-free dilaton gravity action and determine the resulting equations of motion. Consistency is checked by considering the restraint imposed due to invariance of the matter action under simple coordinate transformations, and the special case of N=2 is examined. We also examine a sub-class of theories whereby a Palatini variation dynamically coincides with that of the "ordinary" Hilbert variational principle; in particular we examine a generalized Brans-Dicke theory and the associated role of conformal transformations.Comment: 16 pages, LaTe

Properties of hyperkahler manifolds and their twistor spaces

We describe the relation between supersymmetric sigma-models on hyperkahler manifolds, projective superspace, and twistor space. We review the essential aspects and present a coherent picture with a number of new results.Comment: 26 pages. v2: Sign mistakes corrected; Kahler potential explicitly calculated in example; references added. v3: Published version--several small clarifications per referee's reques

The Semi-Chiral Quotient, Hyperkahler Manifolds and T-duality

We study the construction of generalized Kahler manifolds, described purely in terms of N=(2,2) semichiral superfields, by a quotient using the semichiral vector multiplet. Despite the presence of a b-field in these models, we show that the quotient of a hyperkahler manifold is hyperkahler, as in the usual hyperkahler quotient. Thus, quotient manifolds with torsion cannot be constructed by this method. Nonetheless, this method does give a new description of hyperkahler manifolds in terms of two-dimensional N=(2,2) gauged non-linear sigma models involving semichiral superfields and the semichiral vector multiplet. We give two examples: Eguchi-Hanson and Taub-NUT. By T-duality, this gives new gauged linear sigma models describing the T-dual of Eguchi-Hanson and NS5-branes. We also clarify some aspects of T-duality relating these models to N=(4,4) models for chiral/twisted-chiral fields and comment briefly on more general quotients that can give rise to torsion and give an example.Comment: 31 page

Generalized Kahler manifolds and off-shell supersymmetry

We solve the long standing problem of finding an off-shell supersymmetric formulation for a general N = (2, 2) nonlinear two dimensional sigma model. Geometrically the problem is equivalent to proving the existence of special coordinates; these correspond to particular superfields that allow for a superspace description. We construct and explain the geometric significance of the generalized Kahler potential for any generalized Kahler manifold; this potential is the superspace Lagrangian.Comment: 21 pages; references clarified and added; theorem generalized; typos correcte

Gauged (2,2) Sigma Models and Generalized Kahler Geometry

We gauge the (2,2) supersymmetric non-linear sigma model whose target space has bihermitian structure (g, B, J_{\pm}) with noncommuting complex structures. The bihermitian geometry is realized by a sigma model which is written in terms of (2,2) semi-chiral superfields. We discuss the moment map, from the perspective of the gauged sigma model action and from the integrability condition for a Hamiltonian vector field. We show that for a concrete example, the SU(2) x U(1) WZNW model, as well as for the sigma models with almost product structure, the moment map can be used together with the corresponding Killing vector to form an element of T+T* which lies in the eigenbundle of the generalized almost complex structure. Lastly, we discuss T-duality at the level of a (2,2) sigma model involving semi-chiral superfields and present an explicit example.Comment: 33 page

NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin Remodeling

At a first glance, ribosome biogenesis and chromatin remodeling are quite different processes, but they share a common problem involving interactions between charged nucleic acids and small basic proteins that may result in unwanted intracellular aggregations. The multifunctional nuclear acidic chaperone NPM1 (B23/nucleophosmin) is active in several stages of ribosome biogenesis, chromatin remodeling, and mitosis as well as in DNA repair, replication and transcription. In addition, NPM1 plays an important role in the Myc-ARF-p53 pathway as well as in SUMO regulation. However, the relative importance of NPM1 in these processes remains unclear. Provided herein is an update on the expanding list of the diverse activities and interacting partners of NPM1. Mechanisms of NPM1 nuclear export functions of NPM1 in the nucleolus and at the mitotic spindle are discussed in relation to tumor development. It is argued that the suggested function of NPM1 as a histone chaperone could explain several, but not all, of the effects observed in cells following changes in NPM1 expression. A future challenge is to understand how NPM1 is activated, recruited, and controlled to carry out its functions